Maternal undernutrition and cardiometabolic disease: A latin american perspective

Patricio Lopez-Jaramillo, Diego Gomez-Arbelaez, Aristides Sotomayor-Rubio, Daniel Mantilla-Garcia, Jose Lopez-Lopez

Producción científica: Artículos / NotasArticulo en revista no especializadarevisión exhaustiva

21 Citas (Scopus)

Resumen

The current epidemic of obesity and cardiometabolic diseases in developing countries is described as being driven by socioeconomic inequalities. These populations have a greater vulnerability to cardiometabolic diseases due to the discrepancy between the maternal undernutrition and its consequence, low-birth weight progeny, and the subsequent modern lifestyles which are associated with socioeconomic and environmental changes that modify dietary habits, discourage physical activity and encourage sedentary behaviors. Maternal undernutrition can generate epigenetic modifications, with potential long-term consequences. Throughout life, people are faced with the challenge of adapting to changes in their environment, such as excessive intake of high energy density foods and sedentary behavior. However, a mismatch between conditions experienced during fetal programming and current environmental conditions will make adaptation difficult for them, and will increase their susceptibility to obesity and cardiovascular diseases. It is important to conduct research in the Latin American context, in order to define the best strategies to prevent the epidemic of cardiometabolic diseases in the region.

Idioma originalInglés
Número de artículo41
PublicaciónBMC Medicine
Volumen13
N.º1
DOI
EstadoPublicada - 2 mar. 2015
Publicado de forma externa

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