Gastric mucosa analysis using speckle patterns: A medical diagnosis alternative

Carlos Augusto Andrade Eraso, Mario Milver Patiño Velasco, Jairo Alfonso Vásquez Lopez, Jaury Leon Tellez, Luis Eduardo Bravo, Hector Rabal, Marcelo Trivi

Producción científica: Libro / Capitulo del libro / InformeLibros de Investigaciónrevisión exhaustiva

Resumen

Speckle techniques have been extensively employed in biomedical applications. It has been shown, that these non invasive optical techniques are useful to discriminate healthy tissues from those presenting some type of pathology. In this work we analyze speckle patterns from histological samples of gastric mucosa obtained by means of digestive endoscopies with three different histopathological confirmed diagnoses: atrophy, metaplasia and dysplasia. We studied biopsies from 27 patients and formed groups following the corresponding speckle contrast features. Three different groups according to the speckle contrast were established: higher for intestinal metaplasia, intermediate for gastric dysplasia and low for gastric atrophy. The comparison with histopathology shows a high value of concordance between both tests, making this methodology emerges as a possible new classification system for qualitative and quantitative gastric biopsy using optical techniques.

Idioma originalInglés
Título de la publicación alojada22nd Congress of the International Commission for Optics
Subtítulo de la publicación alojadaLight for the Development of the World
DOI
EstadoPublicada - 2011
Publicado de forma externa
Evento22nd Congress of the International Commission for Optics: Light for the Development of the World - Puebla, México
Duración: 15 ago. 201119 ago. 2011

Serie de la publicación

NombreProceedings of SPIE - The International Society for Optical Engineering
Volumen8011
ISSN (versión impresa)0277-786X

Conferencia

Conferencia22nd Congress of the International Commission for Optics: Light for the Development of the World
País/TerritorioMéxico
CiudadPuebla
Período15/08/1119/08/11

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