@article{fd6ae98116864920ab50ae18e23bfb43,
title = "Antinociceptive and anti-inflammatory effects of Croton malambo bark aqueous extract",
abstract = "Croton malambo (K.) bark aqueous extract, popularly known in Venezuela as {"}palomatias{"} or {"}torco{"} was tested for acute toxicity and for its anti-inflammatory and antinociceptive effects using tail flick and writhing syndrome tests models, respectively. Croton malambo aqueous extract (6.15 mg/kg i.p.) administered intraperitoneally had a significant antinociceptive and anti-inflammatory effects compared to acetylsalicylic acid (200 mg/kg p.o.) and sodium diclofenac (5.64 mg/kg p.o.). Studies to determine correlation between chemical composition and pharmacological activity are underway.",
keywords = "Analgesic, Anti-inflammatory activity, Aqueous extract, Croton malambo",
author = "Su{\'a}rez, {Al{\'i}rica I.} and Compagnone, {Reinaldo S.} and Salazar-Bookaman, {Maria M.} and Stephen Tillett and {Delle Monache}, Franco and {Di Giulio}, Camilo and Gustavo Bruges",
note = "Funding Information: Support for this research was provided in part by a grant from the Consejo de Desarrollo Cient{\'ı}fico y Humanistico de la UCV (Grant No. O6-30-4074-98), CYTED and FONACIT (Venezuela)—CNR (Italy) (Grant No. PI-2001000347). Special thanks to Dr. Antonio Su{\'a}rez, who made a great contribution to this research.",
year = "2003",
month = sep,
day = "1",
doi = "10.1016/S0378-8741(03)00179-X",
language = "Ingl{\'e}s",
volume = "88",
pages = "11--14",
journal = "Journal of Ethnopharmacology",
issn = "0378-8741",
publisher = "Elsevier Ireland Ltd",
number = "1",
}