Adherencia al tratamiento anticoagulante oral por fibrilación auricular no valvular en personas mayores de 65 años

Wiston A. Rodríguez-Rocha, Estephanía Chacón-Valenzuela, Miguel O. Cadena-Sanabria, Miguel E. Ochoa-Vera

Resultado de la investigación: Artículos / NotasArtículo Científicorevisión exhaustiva


Introduction: non-valvular atrial fibrillation is the most common cardiac arrhythmia in the elderly and has been related to different adverse outcomes such as stroke, which in 80% of cases can be prevented with oral anticoagulants, a benefit that is conditioned by an adequate therapeutic adherence. Objective: to determine adherence to anticoagulant treatment in patients older than 65 years with non-valvular atrial fibrillation and associated factors. Methodology: cross-sectional analytical observational study conducted at the FOSCAL anticoagulation clinic. Therapeutic adherence was evaluated using the Moris-ky 8 scale in 102 patients, with an average age of 76 years. Sociodemographic, clinical, geriatric syndrome and health system-related variables were analyzed, then a bivariate analysis was performed. A value of p < 0.05 was accepted as sta-tistical significance. Results: Low pharmacological adherence was found in 42.1%, whose main cause was forgetting to take their medication (50%), likewise, the variables associated with the health system with low adherence were disagreement with the dispatch of the anticoagulant medication (OR: 2.97; 95% CI: 1.1-8.2; p = 0,02) and untimely dispatch (OR: 5.85; CI 95% 1.5-32.8; p = 0,005). Taking antiplatelet agents (p = 0.04) and the presence of polypharmacy (p = 0.04) were associated with moderate and high pharmacological adherence. Conclusions: the prevalence of low adherence to pharmacological treatment is significant. It is necessary to know some aspects of the health system that limit adherence since they impact the effecti-veness of oral antiocogulants in the elderly population.

Título traducido de la contribuciónAdherence to oral anticoagulation in non-valvular atrial fibrillation in patients over 65 years
Idioma originalEspañol
Páginas (desde-hasta)551-558
Número de páginas8
PublicaciónRevista Colombiana de Cardiologia
EstadoPublicada - 1 sep. 2022
Publicado de forma externa

Palabras clave

  • Aged
  • Anticoagulants
  • Atrial fibrillation
  • Therapeutic adherence


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