A Study on the Efficacy and Safety of Pipeline Shield Stents and Nonmodified Surface Flow-Diverting Stents in Patients with Intracranial Aneurysms

Julio García-Núñez, Daniela D Vera, Andrés F. Ortiz, Adriana Rodríguez, Juan José Lara, María José Gomez, Sergio Serrano-Gómez, Adriana Reyes, Carlos Ferreira-Prada, Melquizidel Galvis-Méndez, Oliverio Vargas-Pérez, Daniel E. Mantilla-García

Producción científica: Artículos / NotasArtículo Científicorevisión exhaustiva

Resumen

- BACKGROUND: Few studies have compared the Pipeline Shield stents with previous generations of flowdiverting stents (FDSs) for the treatment of unruptured
intracranial aneurysms. This study aimed to evaluate the
efficacy and safety of Pipeline Shield stents and FDSs
without modified surfaces.
- METHODS: The present evaluation is a retrospective
cohort study of patients endovascularly treated with
Pipeline Shield stents or FDSs without modified surfaces
for unruptured intracranial aneurysms between January
2014 and June 2022. The data analyzed were obtained from
the anonymized database of our institution’s interventional
radiology service.
- RESULTS: A total of 147 patients with 155 unruptured
intracranial aneurysms were included. Of the 155 aneurysms, 96 were treated with Pipeline Shield stents and 59
with FDSs without modified surfaces. The aneurysms
treated with Pipeline Shield stents had higher 6-month
(O’Kelly-Marotta [OKM] D; 87.5% vs. 71.4%; P [ 0.025)
and 1-year (OKM D; 82.5% vs. 63.0%; P [ 0.047) occlusion
rates than the aneurysms treated using FDSs without
modified surfaces. No differences between the devices
were found at the 1-year follow-up in the incidence of
ischemic stroke (P [ 0.939) or hemorrhagic complications
(P [ 0.559).
- CONCLUSIONS: Pipeline Shield stents demonstrated
superior complete occlusion rates (OKM D) at both the 6-
month and the 1-year follow-up assessments compared
with nonmodified surface FDSs. No significant differences
were found in the safety profiles between the 2 types of
stents with regard to thromboembolic complications and
ischemic events. Further research with larger stu
Idioma originalInglés
Páginas (desde-hasta)e781-e786
PublicaciónWorld Neurosurgery
Volumen183
DOI
EstadoPublicada - mar. 2024

Palabras clave

  • Embolization
  • endovascular procedures
  • Hemorrhagic complications
  • Occlusion rates
  • Thromboembolic complications

Líneas de Investigación UNAB

  • Radiología

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