Hiperintensidades de sustancia blanca en pacientes con migraña

Abstract

Introduction: White matter hyperintensities are an increasingly frequent finding in brain magnetic resonance imaging and have been described in numerous pathologies. Its differential diagnosis will depend on the location, morphology and behavior over time and on the different sequences obtained. Some authors have found an association between this finding in magnetic resonance imaging and migraine, which can be explained by changes in the cerebral microvasculature. However, not all texts agree on this, many authors have not found a statistically significant association between these two pathologies. Therefore, the objective of this study is to establish the association between the diagnosis of migraine and white matter hyperintensities in magnetic resonance imaging of patients under 50 years of age with a diagnostic impression of headache at a reference radiological center in Bucaramanga. Methodology: A cross-sectional analytical study was carried out in patients with headache who attended the brain magnetic resonance at our institution between January 2022 and June 2022. All patients under 50 years of age who agreed to participate in the study was included and patients with cardiovascular risk factors such as diabetes mellitus or arterial hypertension and those with already established white matter disease were excluded. Results: During the established period, 70 patients with migraine and 39 patients with other primary headaches, aged between 19 and 49 years, were included. The incidence of white matter hyperintensities was 42%. Patients with white matter hyperintensities were older than those who did not present them (35.2 years vs 31.5 years p 0.02). In the present study, no statistically significant association was found between the presence of migraine and white matter hyperintensities in magnetic resonance, neither with the rest of the variables studied, including the presence or absence of aura, age, location, degree of clinical severity or radiological. Conclusion: It was not possible to find an association between white matter hyperintensities and migraine or with other clinical or radiological variables, unlike other studies published in the literature, therefore, it is necessary to carry out studies with a larger sample in our population to clarify the association between these two entities.

Date of Award	25 Feb 2022
Original language	Spanish (Colombia)
Awarding Institution	Universidad Autónoma de Bucaramanga Facultad de Ciencias de la Salud Especialización Médica y Quirúrgica en Radiología e Imágenes Diagnósticas
Supervisor	Ana Teresa Araújo Reyes (Supervisor), Juan Carlos Mantilla Suarez (Codirector) & Juan Carlos Alberto Uribe Caputi (Asesor)