TY - JOUR
T1 - Veno-Arterial Index (VAI)—A Promising Tool For Identifying Renal Transplant Rejection
AU - Lubinus Badillo, Federico Guillermo
AU - Zuñiga Hadechni, Evelyn Elena
AU - Valenzuela Santos, Diana Maria
AU - Mantilla Suarez, Juan Carlos
AU - Ochoa Vera, Miguel Enrique
AU - Vera Campos, Silvia Nathalia
AU - Villarreal Ibañez, Erick Daniel
AU - Carrillo, Manuela Fernanda
N1 - Publisher Copyright:
© 2021, Society for Vascular Ultrasound.
PY - 2022/3
Y1 - 2022/3
N2 - The objective of this study is to evaluate the veno-arterial index (VAI) as a predictor of renal rejection in kidney transplant patients. A diagnostic test study was conducted between January 2014 and May 2018. Renal transplant patients who underwent percutaneous renal biopsy were included. The VAI was obtained by measuring the flow velocity in the renal segmental vein and dividing this value by the peak systolic velocity of the segmental artery in this same location. The records of 77 patients were analyzed. Among these patients, 32 (42%) were positive for transplant rejection and 29 presented with acute rejection. In patients with renal rejection, the median VAI was 0.67 (interquartile range [IQR] = 0.56-0.87), and in kidneys with a negative biopsy for rejection, the median VAI was 0.41 (IQR = 0.27-0.57), with a statistically significant difference (P =.007) and a value much higher than that obtained for the general population of 0.30 (IQR = 0.18-0.44). Subacute and acute rejected kidneys had an even higher VAI of 0.725 (IQR = 0.57-0.87; P =.0001). Although the resistive index has a good correlation with glomerular filtration, it is not possible by that index to differentiate among the multiple causes that can lead to graft dysfunction. The results of this study show that the VAI might be a useful parameter, which when elevated could predict renal transplant rejection. © 2021, Society for Vascular Ultrasound.
AB - The objective of this study is to evaluate the veno-arterial index (VAI) as a predictor of renal rejection in kidney transplant patients. A diagnostic test study was conducted between January 2014 and May 2018. Renal transplant patients who underwent percutaneous renal biopsy were included. The VAI was obtained by measuring the flow velocity in the renal segmental vein and dividing this value by the peak systolic velocity of the segmental artery in this same location. The records of 77 patients were analyzed. Among these patients, 32 (42%) were positive for transplant rejection and 29 presented with acute rejection. In patients with renal rejection, the median VAI was 0.67 (interquartile range [IQR] = 0.56-0.87), and in kidneys with a negative biopsy for rejection, the median VAI was 0.41 (IQR = 0.27-0.57), with a statistically significant difference (P =.007) and a value much higher than that obtained for the general population of 0.30 (IQR = 0.18-0.44). Subacute and acute rejected kidneys had an even higher VAI of 0.725 (IQR = 0.57-0.87; P =.0001). Although the resistive index has a good correlation with glomerular filtration, it is not possible by that index to differentiate among the multiple causes that can lead to graft dysfunction. The results of this study show that the VAI might be a useful parameter, which when elevated could predict renal transplant rejection. © 2021, Society for Vascular Ultrasound.
KW - blood flow velocity
KW - kidney transplant
KW - renal Doppler
KW - renal duplex ultrasound
KW - renal transplant rejection
KW - blood flow velocity
KW - kidney transplant
KW - renal Doppler
KW - renal duplex ultrasound
KW - renal transplant rejection
UR - http://www.scopus.com/inward/record.url?scp=85121350222&partnerID=8YFLogxK
U2 - 10.1177/15443167211060837
DO - 10.1177/15443167211060837
M3 - Artículo Científico
AN - SCOPUS:85121350222
SN - 1544-3167
VL - 46
SP - 11
EP - 16
JO - Journal for Vascular Ultrasound
JF - Journal for Vascular Ultrasound
IS - 1
ER -
