The effect of bariatric surgery on metabolic syndrome: A retrospective cohort study in Colombia

Gonzalo A. Domínguez Alvarado, María C. Otero Rosales, Julián C. Cala Duran, Sergio Serrano-Gómez, Tania Y. Carrero Barragan, Paula N. Domínguez Alvarado, Martha L. Ramírez, Kamila Serrano-Mesa, Ivan D. Lozada-Martinez, Alexis R. Narvaez-Rojas, Luis E. López Gómez

Research output: Articles / NotesScientific Articlepeer-review

5 Scopus citations


Introduction and Objective: Metabolic syndrome (MetS) represents a group of metabolic abnormalities. It is currently a pandemic, and its prevalence is on the rise. MetS has a direct relationship with obesity, for this reason, bariatric and metabolic surgery has been proposed as a method to simultaneously control obesity and MetS. However, in Colombia the results of this intervention are unknown. This study aims to compare metabolic syndrome before and after bariatric surgery in a Colombian population. Methods: Retrospective cohort study conducted in a highly complex institution in Colombia, where comparing the prevalence of metabolic syndrome in patients who underwent bariatric surgery during a 1-year follow-up period, between January 2015 and December 2019. Of these patients, 48 underwent Roux-en-Y gastric bypass, and 32 underwent sleeve gastrectomy by laparoscopic technique. Results: A total of 80 patients were included, of which 67.5% were women and the mean age was 42.8 ± 12.9 years. The most frequent preprocedure comorbidities were arterial hypertension (36.2%), dyslipidemia (32.4%), and sleep apnea (20%). After bariatric surgery, the prevalence of metabolic syndrome decreased from 66.2% to 3.7% (p < 0.05). In addition, a reduction in the Homeostatic Model Assessment for Insulin Resistance score from 77.5% to 22.5% was observed during the follow-up period. HbA1c, creatinine, and thyroid-stimulating hormone, were the only parameters without significant changes. Conclusions: Metabolic and bariatric surgery is an effective treatment for weight reduction, with a high impact in reducing the prevalence of metabolic syndrome and insulin resistance in the short and medium term in the Colombian population.

Original languageEnglish
Article numbere1090
Pages (from-to)e1090
Number of pages7
JournalHealth Science Reports
Issue number2
StatePublished - 30 Jan 2023


  • bariatric surgery
  • cardiometabolic risk factors
  • colombia
  • metabolic syndrome
  • obesity


Dive into the research topics of 'The effect of bariatric surgery on metabolic syndrome: A retrospective cohort study in Colombia'. Together they form a unique fingerprint.

Cite this