Relación entre la lactancia materna exclusiva los primeros seis meses de vida y el desarrollo de resistencia a la insulina en niños y adolescentes de Bucaramanga, Colombia

Translated title of the contribution: Relationship between exclusive breastfeeding the first six months of life and development of insulin resistance in children and adolescents in Bucaramanga, Colombia

Norma Serrano, Adriana Robles Silva, Diana Paola Suárez, Edna Gamboa-Delgado, Doris Cristina Quintero-Lesmes

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Introduction: exclusive breastfeeding (EB) is a protective factor against the development of insulin resistance (IR) as mainstay of the metabolic syndrome. Objective: the objective of the study was to evaluate the relationship between EB during the first six months of life and the development of IR through the Homeostasis Model Assessment (HOMA-IR) and Quantitative Insulin Sensitivity Check Index (QUICKI) indexes. Material and methods: a population-based cohort study included 494 adolescent participants, from whom socio-demographic, anthropometric, and cardiometabolic variables were assessed using the HOMA-IR and QUICKI indexes to determine the degree of association between EB and the development IR. The results were expressed in medians. Results: the prevalence of EB was 42%. The results suggest a protective effect of EB on IR, in such a way that for each extra month of EB, the HOMA-IR index decreases in 0.32 (p = 0.005) and the index QUICKI increases in 0.70 (p = 0.008). Regarding waist circumference, body mass index and waist size index, this relationship was not significant. Conclusion: the bivariate and multivariate analyses indicate an epidemiologically significant relationship that demonstrates a protective effect of EB on the HOMA-IR and QUICKI indexes.

Translated title of the contributionRelationship between exclusive breastfeeding the first six months of life and development of insulin resistance in children and adolescents in Bucaramanga, Colombia
Original languageSpanish
Pages (from-to)1042-1048
Number of pages7
JournalNutricion Hospitalaria
Volume35
Issue number5
DOIs
StatePublished - 2018
Externally publishedYes

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