Queratitis micótica causada por Scedosporium apiospermum en paciente inmunocompetente

Translated title of the contribution: Mycotic keratitis caused by Scedosporium apiospermum in an immunocompetent patient

V. Galvis, R. Berrospi, A. Tello, D. Ramírez, D. Villarreal

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Clinical case: A 51 year-old immunocompetent male was referred due to presenting with a large corneal ulcer with hypopyon in the right eye. Topical amphotericin B, fluconazole and moxifloxacin, as well as oral itraconazole were initially indicated. Following the report of mycotic structures on staining, topical natamycin was started. The result of the culture was reported two weeks later as, Scedosporium apiospermum (S. apiospermum), and topical voriconazole was then added. The response to treatment was very slow, and took five weeks after receiving triple therapy (natamycin, voriconazole and fluconazole) and one dose of intrastromal voriconazole, for the hypopyon to disappear. The final outcome was successful, achieving healing of the ulcer. The patient is waiting for a corneal transplant. Discussion: A microbiological study is essential in patients in whom fungal keratitis is suspected. The treatment of choice against S. apiospermum is with voriconazole, but the combination of various antifungal agents may be required.

Translated title of the contributionMycotic keratitis caused by Scedosporium apiospermum in an immunocompetent patient
Original languageSpanish
Pages (from-to)613-616
Number of pages4
JournalArchivos de la Sociedad Espanola de Oftalmologia
Volume93
Issue number12
DOIs
StatePublished - Dec 2018

Fingerprint

Dive into the research topics of 'Mycotic keratitis caused by Scedosporium apiospermum in an immunocompetent patient'. Together they form a unique fingerprint.

Cite this