Major Cardiovascular Risk Factors in Latin America: A Comparison with the United States. The Latin American Consortium of Studies in Obesity (LASO)

J. Jaime Miranda, Victor M. Herrera, Julio A. Chirinos, Luis F. Gómez, Pablo Perel, Rafael Pichardo, Angel González, José R. Sánchez, Catterina Ferreccio, Ximena Aguilera, Eglé Silva, Myriam Oróstegui, Josefina Medina-Lezama, Cynthia M. Pérez, Erick Suárez, Ana P. Ortiz, Luis Rosero, Noberto Schapochnik, Zulma Ortiz, Daniel FerranteJuan P. Casas, Leonelo E. Bautista

Research output: Articles / NotesScientific Articlepeer-review

96 Scopus citations

Abstract

Background: Limited knowledge on the prevalence and distribution of risk factors impairs the planning and implementation of cardiovascular prevention programs in the Latin American and Caribbean (LAC) region. Methods and Findings: Prevalence of hypertension, diabetes mellitus, abnormal lipoprotein levels, obesity, and smoking were estimated from individual-level patient data pooled from population-based surveys (1998-2007, n = 31,009) from eight LAC countries and from a national survey of the United States (US) population (1999-2004) Age and gender specific prevalence were estimated and age-gender adjusted comparisons between both populations were conducted. Prevalence of diabetes mellitus, hypertension, and low high-density lipoprotein (HDL)-cholesterol in LAC were 5% (95% confidence interval [95% CI]: 3.4, 7.9), 20.2% (95% CI: 12.5, 31), and 53.3% (95% CI: 47, 63.4), respectively. Compared to LAC region's average, the prevalence of each risk factor tended to be lower in Peru and higher in Chile. LAC women had higher prevalence of obesity and low HDL-cholesterol than men. Obesity, hypercholesterolemia, and hypertriglyceridemia were more prevalent in the US population than in LAC population (31 vs. 16.1%, 16.8 vs. 8.9%, and 36.2 vs. 26.5%, respectively). However, the prevalence of low HDL-cholesterol was higher in LAC than in the US (53.3 vs. 33.7%). Conclusions: Major cardiovascular risk factors are highly prevalent in LAC region, in particular low HDL-cholesterol. In addition, marked differences do exist in this prevalence profile between LAC and the US. The observed patterns of obesity-related risk factors and their current and future impact on the burden of cardiovascular diseases remain to be explained.

Original languageEnglish
Article numbere54056
JournalPLoS ONE
Volume8
Issue number1
DOIs
StatePublished - 17 Jan 2013

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