Incretin analogs and inhibitors of DPP-4: Which is their role in the primary prevention of cardiovascular diseases?

Patricio López-Jaramillo, Carlos Velandia, Gabriela Castillo, Tatiana Sánchez, Julie Álvarez

Research output: Articles / NotesArticle in a non-specialized journalpeer-review

4 Scopus citations

Abstract

Type 2 diabetes mellitus (T2DM) is a highly prevalent disease, which has shown a rapid increase in recent decades, doubling the number of people with this disease. Several epidemiological studies show that 70% of diabetes deaths are caused by cardiovascular events (coronary heart disease and stroke). Recently there has been an expansion in the discovery of drugs for the management of type 2 diabetes. These drugs must demonstrate additional cardiovascular system benefi ts before its introduction in the market. This paper aims to determine the role of new antidiabetic drugs that act on the incretin system and its effects on the primary prevention of cardiovascular events.

Translated title of the contributionAnálogos de incretina e inhibidores de la DPP-4: ¿qué papel desempeñan en la prevención primaria de las enfermedades cardiovasculares?
Original languageEnglish
Pages (from-to)287-299
Number of pages13
JournalRevista Colombiana de Cardiologia
Volume20
Issue number5
DOIs
StatePublished - 2013
Externally publishedYes

Keywords

  • Cardiovascular disease
  • Diabetes
  • Inhibitors
  • Pharmacology

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