Hiperglucemia se asocia a mayor número de desenlaces adversos en individuos latinoamericanos con infarto agudo de miocardio

Translated title of the contribution: Hyperglycaemia is associated with worse outcomes in Latin-American individuals with acute myocardial infarction

Diego Gomez-Arbelaez, Gregorio Sánchez-Vallejo, Maritza Perez, Ronald Gerardo Garcia, Jhon Freddy Arguello, Ernesto Peñaherrera, Yan Carlos Duarte, Maria Eugenia Casanova, Jose Luis Accini, Aristides Sotomayor, Paul Anthony Camacho, Patricio Lopez-Jaramillo

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

Background: Alterations in glucose metabolism have been reported as risk and poor prognostic factors for acute myocardial infarction (AMI); however in Latin-American population this information is limited. Thus, an evaluation was performed on the association between glycaemic status and short- and long-term outcomes in patients with a first AMI. Methods: A multicentre, prospective, observational, cohort study was conducted in 8 hospitals from Colombia and Ecuador. Results: A total of 439 patients with confirmed AMI were included, of which 305 (69.5%) had prediabetes or type 2 diabetes mellitus (DM2). Compared with normal glycaemia group, patients with known DM2 had greater risk of prolonged hospital stay (HR: 2.60, 95% CI: 1.38-4.92, P = .003), Killip class iii/. iv (HR: 9.46, 95% CI: 2.20-40.62, P = .002), and in-hospital heart failure (HR: 10.76, 95% CI: 3.37-34.31, P < .001). Patients with prediabetes, new DM2, and known DM2 showed higher rates of major adverse cardiovascular events after 3 years follow-up. Conclusion: Glucose metabolism abnormalities have an important significance in the short- and long-term prognosis in Latin-American patients that survive a first AMI.

Translated title of the contributionHyperglycaemia is associated with worse outcomes in Latin-American individuals with acute myocardial infarction
Original languageSpanish
Pages (from-to)9-18
Number of pages10
JournalClinica e Investigacion en Arteriosclerosis
Volume28
Issue number1
DOIs
StatePublished - 1 Jan 2016
Externally publishedYes

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