Gastric mucosa analysis using speckle patterns: A medical diagnosis alternative

Carlos Augusto Andrade Eraso, Mario Milver Patiño Velasco, Jairo Alfonso Vásquez Lopez, Jaury Leon Tellez, Luis Eduardo Bravo, Hector Rabal, Marcelo Trivi

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Speckle techniques have been extensively employed in biomedical applications. It has been shown, that these non invasive optical techniques are useful to discriminate healthy tissues from those presenting some type of pathology. In this work we analyze speckle patterns from histological samples of gastric mucosa obtained by means of digestive endoscopies with three different histopathological confirmed diagnoses: atrophy, metaplasia and dysplasia. We studied biopsies from 27 patients and formed groups following the corresponding speckle contrast features. Three different groups according to the speckle contrast were established: higher for intestinal metaplasia, intermediate for gastric dysplasia and low for gastric atrophy. The comparison with histopathology shows a high value of concordance between both tests, making this methodology emerges as a possible new classification system for qualitative and quantitative gastric biopsy using optical techniques.

Original languageEnglish
Title of host publication22nd Congress of the International Commission for Optics
Subtitle of host publicationLight for the Development of the World
DOIs
StatePublished - 2011
Event22nd Congress of the International Commission for Optics: Light for the Development of the World - Puebla, Mexico
Duration: 15 Aug 201119 Aug 2011

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume8011
ISSN (Print)0277-786X

Conference

Conference22nd Congress of the International Commission for Optics: Light for the Development of the World
Country/TerritoryMexico
CityPuebla
Period15/08/1119/08/11

Keywords

  • atrophy
  • digital analysis of images
  • dysplasia
  • gastric mucosa
  • laser
  • metaplasia
  • Speckle

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