Flow Diverter Treatment for Non-Ruptured Carotid Aneurysms: Efficacy and Safety

Orlando López-Callejas, Andres F. Ortiz-Giraldo, Daniela D. Vera, Diego A. Ramirez-Rojas, Ana B. Villamizar-Barahona, Carlos A. Ferreira-Prada, Melquizidel Galvis, Oliverio Vargas-Pérez, Sergio Serrano-Gómez, Adriana Reyes-Gonzalez, Daniel Mantilla

Research output: Articles / NotesScientific Articlepeer-review

2 Scopus citations

Abstract

Purpose: Internal carotid artery (ICA) aneurysm treatment with a flow diverter (FD) has shown an adequate efficacy and safety profile, presenting high complete occlusion or near occlusion rates with low complications during follow-up. The purpose of this study was to evaluate the efficacy and safety of FD treatment in non-ruptured internal carotid aneurysms. Materials and Methods: This is a retrospective, single-center, observational study evaluating patients diagnosed with unruptured ICA aneurysms treated with an FD between January 1, 2014, and January 1, 2020. We analyzed an anonymized database. The primary effectiveness endpoint was complete occlusion (O’Kelly–Marotta D, OKM-D) of the target aneurysm through 1-year follow-up. The safety endpoint was the evaluation of modified Rankin Scale (mRS) 90 days after treatment, considering a favorable outcome an mRS 0-2. Results: A total of 106 patients were treated with an FD, 91.5% were women; the mean follow-up was 427.2±144.8 days. Technical success was achieved in 105 cases (99.1%). All patients included had 1-year follow-up digital subtraction angiography control; 78 patients (73.6%) completed the primary efficacy endpoint by achieving total occlusion (OKM-D). Giant aneurysms had a higher risk of not achieving complete occlusion (risk ratio, 3.07; 95% confidence interval, 1.70-5.54]). The safety endpoint of mRS 0-2 at 90 days was accomplished in 103 patients (97.2%). Conclusion: Treatment of unruptured ICA aneurysms with an FD showed high 1-year total occlusion results, with very low morbidity and mortality complications.

Original languageEnglish
Pages (from-to)23-29
Number of pages7
JournalNeurointervention
Volume18
Issue number1
DOIs
StatePublished - Mar 2023

Keywords

  • Aneurysm
  • Complications
  • Endovascular procedures
  • Safety
  • Stents
  • Treatment outcome

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