Complex Congenital Heart Disease and Neurodevelopment. A Case Study of Fraternal Twins

María Paula Silva Sánchez; Jesús David Peña Hernández; Luz Stella Pinilla García; Gustavo Adolfo Contreras García; Mario Augusto Rojas; Luis Alfonso Díaz Martínez

doi:10.1080/87565641.2022.2070169

Complex Congenital Heart Disease and Neurodevelopment. A Case Study of Fraternal Twins

María Paula Silva Sánchez, Jesús David Peña Hernández, Luz Stella Pinilla García, Gustavo Adolfo Contreras García, Mario Augusto Rojas, Luis Alfonso Díaz Martínez

Research output: Articles / Notes › Scientific Article › peer-review

Abstract

Congenital heart defects have been associated with adverse neurodevelopmental outcomes due to factors that result in a hypoxic-ischemic cerebral cumulative effect. We present a pair of fraternal twins: the first twin was healthy, and the second was born with a complex congenital heart defect (CCHD). They were followed for growth and neurodevelopmental outcomes to determine the comparative effect of exposure to a CCHD. Results show that exposure to a CCHD could be related to a persistent motor deficiency with hypotonia and concurrent height for age delay. CCHD requires a comprehensive neurodevelopmental approach; the pathophysiology and the surrounding stimuli are influential.

Original language	English
Pages (from-to)	226-232
Number of pages	7
Journal	Developmental Neuropsychology
Volume	47
Issue number	4
DOIs	https://doi.org/10.1080/87565641.2022.2070169
State	Published - 2022
Externally published	Yes

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10.1080/87565641.2022.2070169

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title = "Complex Congenital Heart Disease and Neurodevelopment. A Case Study of Fraternal Twins",

abstract = "Congenital heart defects have been associated with adverse neurodevelopmental outcomes due to factors that result in a hypoxic-ischemic cerebral cumulative effect. We present a pair of fraternal twins: the first twin was healthy, and the second was born with a complex congenital heart defect (CCHD). They were followed for growth and neurodevelopmental outcomes to determine the comparative effect of exposure to a CCHD. Results show that exposure to a CCHD could be related to a persistent motor deficiency with hypotonia and concurrent height for age delay. CCHD requires a comprehensive neurodevelopmental approach; the pathophysiology and the surrounding stimuli are influential.",

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T1 - Complex Congenital Heart Disease and Neurodevelopment. A Case Study of Fraternal Twins

AU - Silva Sánchez, María Paula

AU - Peña Hernández, Jesús David

AU - Pinilla García, Luz Stella

AU - Contreras García, Gustavo Adolfo

AU - Rojas, Mario Augusto

AU - Díaz Martínez, Luis Alfonso

PY - 2022

Y1 - 2022

N2 - Congenital heart defects have been associated with adverse neurodevelopmental outcomes due to factors that result in a hypoxic-ischemic cerebral cumulative effect. We present a pair of fraternal twins: the first twin was healthy, and the second was born with a complex congenital heart defect (CCHD). They were followed for growth and neurodevelopmental outcomes to determine the comparative effect of exposure to a CCHD. Results show that exposure to a CCHD could be related to a persistent motor deficiency with hypotonia and concurrent height for age delay. CCHD requires a comprehensive neurodevelopmental approach; the pathophysiology and the surrounding stimuli are influential.

AB - Congenital heart defects have been associated with adverse neurodevelopmental outcomes due to factors that result in a hypoxic-ischemic cerebral cumulative effect. We present a pair of fraternal twins: the first twin was healthy, and the second was born with a complex congenital heart defect (CCHD). They were followed for growth and neurodevelopmental outcomes to determine the comparative effect of exposure to a CCHD. Results show that exposure to a CCHD could be related to a persistent motor deficiency with hypotonia and concurrent height for age delay. CCHD requires a comprehensive neurodevelopmental approach; the pathophysiology and the surrounding stimuli are influential.

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M3 - Artículo Científico

C2 - 35506644

AN - SCOPUS:85132651136

SN - 8756-5641

VL - 47

SP - 226

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JO - Developmental Neuropsychology

JF - Developmental Neuropsychology

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Complex Congenital Heart Disease and Neurodevelopment. A Case Study of Fraternal Twins

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