Clinical impact of Sim & Size® simulation software in the treatment of patients with cerebral aneurysms with flow-diverter Pipeline stents

Daniel Mantilla, Carlos A. Ferreira-Prada, Melquisedec Galvis, Oliverio Vargas, Carolina Valenzuela-Santos, Piergiorgio Canci, Miguel Ochoa, Franck Nicoud, Vincent Costalat

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: This study evaluated the clinical impact of the Sim&Size® simulation software on the endovascular treatment with flow-diverter stents of patients with unruptured saccular intracranial aneurysms. Methods: This monocentric retrospective study evaluated a cohort of patients treated with flow-divert stents between June 1, 2014, and December 31, 2019, for cerebral aneurysms. Patients belonged to two groups, patients treated with and without the Sim&Size® simulation software. Univariate, bivariate, and multivariate analyses were used to evaluate the clinical impact of simulation software. Results: Out of the 73 interventions involving 68 patients analyzed by the study, 76.7% were simulated using the Sim&Size® simulation software, and 23.3% were not. Patients treated with the simulation software had shorter stent lengths (16.00 mm vs. 20.00 mm p-value = 0.001) and surgical time (100.00 min vs. 118.00 min p-value = 0.496). Also, fewer of them required more than one stent (3.6% vs. 17.6% p-value = 0.079). Three patients belonging to the non-stimulated group presented hemorrhagic complications. Conclusions: Using the Sim&Size® simulation software for the endovascular treatment of intracranial aneurysms with pipeline flow-diverter stents reduces the stent length.

Original languageEnglish
JournalInterventional Neuroradiology
DOIs
StateAccepted/In press - 2021

Keywords

  • Artificial Intelligence
  • Computer Simulation
  • Endovascular Procedures
  • Flow-Diverter Devices
  • Intracranial Aneurysm
  • Pipeline Embolization Device

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