Analisis de conglomerado de cancer infantil y su relacion con proximidad a fuentes de contaminacion industrial en el Area Metropolitana del Valle de Aburra, 2000-2015

Translated title of the contribution: Cluster analysis of childhood cancer and its relationship with proximity to sources of industrial pollution in the Valle de Aburra Metropolitan Area, 2000-2015

Laura Andrea Rodriguez-Villamizar, Ana Maria Valbuena-Garcia, Feisar Enrique Moreno-Corzo, Maria Alejandra Jaimes-Reyes, Mary Ruth Brome-Bohorquez, Hector Ivan Garcia-Garcia

Research output: Contribution to journalArticlepeer-review

Abstract

Objective: This study evaluated the effect of proximity to industrial sources of air pollution on the occurrence of clusters of childhood cancer cases in the Aburra Valley Metropolitan Area, Department of Antioquia, during the 2000-2015 period. Methodology: The information on childhood cancer cases in children under 15 years of age residing in the metropolitan area was obtained from the Registro Poblacional de Cancer de Antioquia (Antioquia Cancer Population Registry) for that period. 32 industrial clusters were identified based on the local environmental authority's inventory. Local and targeted Kulldorff's circular scan tests were performed to detect childhood cancer clusters in the municipalities and surrounding the industrial clusters, respectively. We used a multivariate regression model adjusted for socioeconomic strata to assess the effect of spatial variables. Results: The specific incidence rate in the Aburra Valley for the evaluated period was 117.13 cases per million children under 15 years of age. The highest incidence rates occurred in the municipalities of Medellín and Sabaneta. The Kulldorff test identified 12 spatial clusters and 8 space-time clusters that were statistically significant in 7 municipalities, particularly in Bello and Medellín. The targeted tests identified childhood cancer clusters surrounding 20 industrial clusters. In multivariate models, an industrial cluster in Bello showed a statistically significant inverse association between incidence and distance from the industrial cluster toward the southeast.

Translated title of the contributionCluster analysis of childhood cancer and its relationship with proximity to sources of industrial pollution in the Valle de Aburra Metropolitan Area, 2000-2015
Original languageSpanish
Article numbere346065
JournalRevista Facultad Nacional de Salud Publica
Volume40
Issue number2
DOIs
StatePublished - 1 May 2022
Externally publishedYes

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